Wan L# … Wen H#, Allis CD#. 2020. Impaired cell fate through gain-of-function mutations in a chromatin reader. Nature.
Wan L*, Wen H*, Li Y* et al. 2017. ENL links histone acetylation to oncogenic gene expression in AML. Nature.
Li Y*, Wen H* et al. 2014. AF9 YEATS domain links histone acetylation to DOT1L-mediated H3K79 methylation. Cell.
Wen H*, #, Li Y*, Xi Y*…Li W#, Li H#, Shi X#. 2014. ZMYND11 links histone H3.3 K36 trimethylation to transcription elongation and tumor suppression. Nature.
Postdoctoral fellow position available
A postdoctoral fellow position is available immediately in the Wen Lab, which is focused on the study of epigenetic regulation of chromatin and transcription in cancer development. The long-term goal of the lab is to understand the molecular mechanisms by which histone modifications regulate chromatin and transcription, and how dysregulation of histone modification homeostasis leads to human cancers. Read the full posting here.
Wen Lab publishes new paper in Nature
The Wen Lab’s latest paper, Impaired cell fate through gain-of-function mutations in a chromatin reader, has been published in Nature! Read it here.